The manufacturing world is in the middle of a worldwide rapid transformation. Planetary urgencies, new production needs and constantly changing standards are just a few of the factors that are driving the industry into a new augmented dimension. This is the starting point of an ambitious project, carried on by the architectural and digital design studio Calibro Zero for CIM 4.0 (Competence Industry Manufacturing), an Italian excellence center realizing and promoting educational and open innovation programs to help Italian enterprises in their transition towards the industry 4.0. The design concerns the reuse of a former educational space in the city of Turin for the realization of a pilot line dedicated to digital manufacturing: a highly innovative space, both in structural and programmatic terms, in which small and medium enterprises can test their products and processes before going to the market. To achieve this goal, Calibro Zero has questioned consolidated spatial divisions based on typological functions and categorizations, hosting a hybridization of different functions in a single space: from the exhibition space to small industrial production, from office activities to the experimental laboratories up to training and educational activities. The design revolves around concepts such as reconfigurability, flexibility, and humanization of the production space, combining typically industrial spatial and material strategies with inspirations derived from the domestic and theatrical world. Thus, the new Digital Pilot Line is characterized by a recognizable image that represents the CIM 4.0 brand and the values of which the Competence Center is the bearer.